If you want to open an OST file in Outlook, the easiest and safest way is to convert it to PST format using eSoftTools OST to PST Converter software. Outlook does not allow direct opening of orphaned or inaccessible OST files, but this tool helps you recover OST data such as emails, contacts, calendars, and attachments and convert them into a PST file, which Outlook supports. This software works with all Outlook versions, maintains data integrity, and provides a user-friendly interface for both technical and non-technical users. After conversion, you can easily import the PST file into Outlook without any data loss.
Read More:- Open an OST file to Outlook
 
You cannot open an OST file directly in Outlook like a PST file because OST files are linked to a specific Outlook profile and Exchange/Office 365 account. Outlook only opens an OST file when it is connected to the same account that originally created it.
Method 1: Open OST with the Original Account (If Available)
If the Exchange or Office 365 account still exists:
  1. Configure the same email account in Outlook.
  2. Outlook will automatically recreate and link the OST file.
  3. Your mailbox data will sync and become accessible.
This method will not work if the account is deleted, inaccessible, or the OST file is orphaned.
Method 2: Convert OST to PST (Recommended)
If the original account is unavailable, the only practical solution is to convert the OST file to PST format using a professional OST to PST converter. Once converted:
  1. Open Outlook.
  2. Go to File → Open & Export → Import/Export.
  3. Import the converted PST file into Outlook.
This method works for orphaned, corrupted, or inaccessible OST files and does not require an Exchange or Office 365 connection.
Conclusion
OST files cannot be opened independently in Outlook. To access the data safely and permanently, converting OST to PST is the most reliable and widely used solution.

More Info: Free Unlimited OST to PST Converter
 
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